If you're looking for a top pot stock to invest in, your search needs to start in the U.S. cannabis market, which boasts many fast-growing companies that are performing incredibly well and that could be excellent buys for years to come.

Three companies that look poised to battle for supremacy in the industry include Curaleaf Holdings (OTC:CURLF)Trulieve Cannabis (OTC:TCNNF), and Cresco Labs (OTC:CRLBF). And if all goes as expected, they will all reach the $1 billion mark in revenue as early as next year.

People in a meeting make a sales presentation.

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1. Curaleaf

Curaleaf is already on track to deliver more than $1 billion in revenue over the next 12 months. In its latest results, released May 10, the company reported sales of $260 million for the period ending March 31. Even if its sales were to remain constant at that number for the next three quarters, its top line would comfortably come in at more than $1 billion. But it's likely it will blow past that mark, as revenue was up 13% from the previous period and the company continues to expand its business.

Its most recent move was the $67 million acquisition of Colorado-based cannabis company Los Suenos. In addition to expanding its reach within that state, the deal will also help bring the company's costs down, as Los Suenos has the largest outdoor growing operation in Colorado. That will help Curaleaf generate better margins and potentially be more competitive on price.

But I wouldn't be surprised if Curaleaf makes at least one more big move beyond this, especially since multistate operator Trulieve may well become the largest cannabis company in the country when it integrates Harvest Health into its operations in a transaction that could close as early as the third quarter of this year.

If your priority is sheer growth, then Curaleaf is the pot stock for you. Its aggressive growth strategy makes it a safe bet that the company will continue exploring every possibility to add to its top line.

2. Trulieve

On its own, Trulieve may still have been able to reach $1 billion in sales next year. But with the acquisition of Harvest Health, it's a lock to do so. For the first three months of 2021, Harvest Health generated $89 million in revenue, putting it at an annual run rate of $356 million in sales. Add that to the $619 million in revenue that Trulieve has posted over the past 12 months and the combined business is nearly at $1 billion without even factoring in any growth.

And as with Curaleaf, a zero-growth year just isn't likely. Harvest Health operates in Arizona, which began selling recreational marijuana earlier this year, and the new segment of the market will only strengthen sales for cannabis operators in that state. Trulieve, meanwhile, is growing its presence in other states, including Pennsylvania, West Virginia, and Massachusetts. 

This pot stock is a great buy if your focus is on profitability. While Curaleaf is profitable on an adjusted EBITDA basis, Trulieve reported an unadjusted net profit of $30 million in its most recent quarterly results. 

3. Cresco Labs

Cresco Labs has the most work to do of the three stocks here to reach the $1 billion mark. However, management believes it can get there by the end of this fiscal year, making that claim in its first-quarter results released May 27. Sales for the period ending March 31 totaled $178 million, which would put it on a run rate of just $712 million for a full year.

The company noted in the earnings release that it is banking on both organic growth and mergers and acquisitions to boost its sales numbers this year. One of those moves includes the expansion of its product base. In June, Cresco announced that it would be adding vape and edible products to its Good News brand and that the products would be available in California, Illinois, and Michigan.

One of the bigger moves the company has made of late was the acquisition of Florida-based Bluma Wellness, which it completed in April. Through Bluma, Cresco will now compete head-on with both Trulieve and Curaleaf for market share in the Sunshine State. As one of the top four states in terms of revenue last year, Florida should open up significant growth opportunities and go a long way toward padding Cresco's top line.

If you're a fan of the underdog or just want a reasonably cheap stock, Cresco might be the option for you. Trading at a price-to-sales multiple of less than 5, the stock is cheaper than both Curaleaf and Trulieve, which trade at more than 10 and 7 times revenue, respectively.

This article represents the opinion of the writer, who may disagree with the “official” recommendation position of a Motley Fool premium advisory service. We’re motley! Questioning an investing thesis -- even one of our own -- helps us all think critically about investing and make decisions that help us become smarter, happier, and richer.