What happened
Shares of Legend Biotech (LEGN -3.34%) dropped 17.6% on Wednesday, falling more than $4 from the day before, though all the action came early. The stock, which closed at $48.54 on Tuesday, opened at $44 a share on Wednesday and fell to $39.37 early in the day before rebounding a bit. The stock is up 46% year to date.
So what
Investors reacted to the company's announcement on Tuesday that the clinical-stage biotech company intends to offer and sell $300 million of American depositary shares, each equaling two ordinary shares, in a public offering. This waters down the stock's value to current investors.
The company is slowly growing revenue, but because of rising costs, is still losing money.
In the third quarter, the company reported revenue of $16.9 million, up 44% year over year. Through nine months, the company reported revenue of $50.8 million, up 45% over the same period last year. However, Legend also said it had a net loss of $124.8 million, or $0.43 a share, compared to $66.5 million and $0.25 a share, year over year. Over nine months, the company lost $297.9 million, or $1.07 per share compared to $245.7 million and $1.08 a share in the same period a year ago.
Now what
Legend is one of several companies looking at chimeric antigen receptor T-cell therapies to target B-cell maturation antigens (BCMA) to treat multiple myleloma, a cancer affecting plasma cells in bone marrow. Multiple myeloma is responsible for 10% of blood-related cancers.
On Monday, Legend fell from $51.06 to $50.67 despite announcing positive news regarding its Phase 1b-2 CARTITUDE-1 study of ciltacabtagene autoleucel (cilta-cel). The drug is a CAR T-cell therapy seen as a potential one-time treatment for multiple myeloma. The company said the treatment showed a 98% overall response rate and 83% stringent complete response rate after almost two years of follow-up on trial participants.
A concern for Legend is that larger, better-funded companies such as Bristol Myers Squibb, Amgen, and Janssen, a subsidiary of Johnson & Johnson, are also targeting BCMA to treat multiple myeloma.
One positive for Legend is it has several therapies in phase 2 and phase 3 trials, meaning it could, in the coming year or two, get a positive influx of revenue.